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Mechanism of opioid-induced pupillary effects   Category: Critical Care   Larson, MD, Mechanism of opioid-induced pupillary effects., Clin Neurophysiol. 2008 Apr 6   OBJECTIVE: This study tested the hypothesis that increased activity in the pupilloconstrictor nucleus by the addition of ambient light and by the administration of fentanyl, sufficient to block pupillary reflex dilation, constricts...

Pupillometry in anesthesia and critical care.   Category: Critical Care   Payen J, Isnardon S, Lavolaine J, Bouzat P, Vinclair M, Francony G, Pupillometry in anesthesia and critical care., Annales francaises d’anesthesie et de reanimation, 2012 June   Abstract Pupil size reflects the balance between sympathetic and parasympathetic systems. Due to technological advances,...

Pupillary Effects of High-dose Opioid Quantified with Infrared Pupillometry   Category: Critical Care   Mark D. Rollins, M.D., Ph.D., John R. Feiner, M.D., Jessica M. Lee, M.D., Sameer Shah, M.D., Merlin Larson, M.D.   ABSTRACT Background: The pupillary light reflex is a critical component of the neurologic examination, yet whether it is present, depressed, or absent...

Pupillometric analysis of the 'absent light reflex’   Category: Critical Care   Larson MD, Muhiudeen I., Pupillometric analysis of the 'absent light reflex'., Arch Neurol. 1995 Apr;52(4):369-72.   OBJECTIVE: To measure the "absent light reflex" with an infrared pupillometer. SETTING: Intensive care unit of the Moffitt-Long Hospitals at the University of California-San Francisco....

Infrared pupillometry during uncal herniation   Category: Critical Care   Manley GT, Larson MD., Infrared pupillometry during uncal herniation., J Neurosurg Anesthesiol. 2002 Jul;14(3):223-8.   Infrared pupillary scans have been used extensively as an objective measure of pupillary reflexes during pharmacological studies of human subjects, but no previous scans have documented the pupillary...

Quantitative pupillometry, a new technology: normative data and preliminary observations in patients with acute head injury   Category: Critical Care   Taylor WR, Chen JW, Meltzer H, Gennarelli TA, Kelbch C, Knowlton S, Richardson J, Lutch MJ, Farin A, Hults KN, Marshall LF., Quantitative pupillometry, a new technology: normative...

Pupillary evaluation for differential diagnosis of coma   Category: Critical Care   Tokuda Y, Nakazato N, Stein GH., Pupillary evaluation for differential diagnosis of coma., Postgrad Med J. 2003 Jan;79(927):49-51.   OBJECTIVES: To determine the usefulness of bedside evaluation of pupils in determining the aetiology of coma by adopting a probabilistic approach. PATIENTS...

Interrater reliability in pupillary measurement   Category: Critical Care   Witting MD, Goyal D., Interrater reliability in pupillary measurement., Ann Emerg Med. 2003 Jun;41(6):832-7.   STUDY OBJECTIVE: A previous report documented ranges of normal pupil size on the basis of measurements by the principal investigator. In this report, we examine interrater reliability of...

Validity of simple measurement to diagnose pupillary dilation   Category: Critical Care   Witting MD., Validity of simple measurement to diagnose pupillary dilation., Am J Emerg Med. 2005 Mar;23(2):155-8.   Abstract Abstract Study Objective: The aim of the study was to compare the validity of 3 methods of detecting pupillary dilation: bright-light...